Wine PyQt5 Alternatives

Wine PyQt5 is described as 'User Interface for Managing Wine' and is an app. There are more than 25 alternatives to Wine PyQt5 for a variety of platforms, including Linux, Mac, Flathub, Wine and Flatpak apps. The best Wine PyQt5 alternative is Wine, which is both free and Open Source. Other great apps like Wine PyQt5 are RetroArch, Lutris, Proton and PlayOnLinux - PlayOnMac.

More about Wine PyQt5

Wine PyQt5 alternatives page was last updated Jun 15, 2025

WineGUI
11 likes
At last, a user-friendly WINE graphical interface.
42 WineGUI alternatives
Cost / License
Free
Open Source (AGPL-3.0)
Application type
Compatibility Layer Tool
Platforms
Linux
Wine
Is WineGUI a good alternative to Wine PyQt5?
WinApps
8 likes
Run Windows apps such as Microsoft Office/Adobe in Linux (Ubuntu/Fedora) and GNOME/KDE as if they were a part of the native OS, including Nautilus integration.
38 WinApps alternatives
Cost / License
Free
Open Source
Application type
Compatibility Layer Tool
Platforms
Linux
Is WinApps a good alternative to Wine PyQt5?
ProtonPlus
5 likes
A simple Wine and Proton-based compatibility tools manager.
Cost / License
Free
Open Source (GPL-3.0)
Application type
Compatibility Layer Tool
Origin
Canada
Platforms
Linux
Arch Linux
Flathub
Fedora
Nix Package Manager
Wine
Flatpak
Vala
Proton
Is ProtonPlus a good alternative to Wine PyQt5?
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ProtonUp-Qt
5 likes
Install and manage GE-Proton, Luxtorpeda & more for Steam and Wine-GE & more for Lutris with this graphical user interface.
40 ProtonUp-Qt alternatives
Cost / License
Free
Open Source (GPL-3.0)
Application type
Compatibility Layer Tool
Origin
Norway
Platforms
Linux
AppImageHub
Arch Linux
Flathub
Flatpak
Is ProtonUp-Qt a good alternative to Wine PyQt5?
Faugus Launcher
3 likes
A simple and lightweight app for running Windows games using UMU-Launcher.
54 Faugus Launcher alternatives
Cost / License
Free
Open Source (MIT)
Platforms
Linux
Flathub
Flatpak
+1
Is Faugus Launcher a good alternative to Wine PyQt5?
WineBottler
29 likes
WineBottler is an App to manage and wrap your Windows apps into convenient OS X apps. WineBottler helps you with running Windows programs on OS X.
35 WineBottler alternatives
Cost / License
Free
Open Source
Application type
Compatibility Layer Tool
Origin
Germany
EU
Alerts
Discontinued
Platforms
Mac
Wine
+1
Is WineBottler a good alternative to Wine PyQt5?
Protontricks
4 likes
A wrapper that does winetricks things for Proton enabled games, requires Winetricks.
Cost / License
Free
Open Source (GPL-3.0)
Application type
Compatibility Layer Tool
Platforms
Linux
Flathub
Python
Flatpak
Is Protontricks a good alternative to Wine PyQt5?
Goldberg Emulator
7 likes
Steam emulator that emulates steam online features. Lets you play games that use the steam multiplayer APIs on a LAN without steam or an internet connection.
33 Goldberg Emulator alternatives
Cost / License
Free
Open Source
Application type
Compatibility Layer Tool
Platforms
Windows
Linux
Steam
Is Goldberg Emulator a good alternative to Wine PyQt5?
Q4wine
20 likes
Q4Wine is a qt4 GUI for wine that will help you manage wine prefixes and installed applications
38 Q4wine alternatives
Cost / License
Free
Open Source (GPL-3.0)
Application type
Compatibility Layer Tool
Platforms
Mac
Linux
BSD
Wine
+1
Is Q4wine a good alternative to Wine PyQt5?
Phoenicis
3 likes
Phoenicis is a graphical front-end for Wine, a tool to help Linux and Mac users run games and programs for Windows. The future of PlayOnLinux and PlayOnMac.
Cost / License
Free
Open Source (LGPL-3.0)
Application type
Compatibility Layer Tool
Alerts
Discontinued
Platforms
Mac
Linux
Flathub
Is Phoenicis a good alternative to Wine PyQt5?
Proton GE
3 likes
This is my build of Proton with the most recent bleeding-edge Proton Experimental WINE.
Cost / License
Free
Open Source
Application type
Compatibility Layer Tool
Origin
United States
Platforms
Linux
Wine
Is Proton GE a good alternative to Wine PyQt5?
MiceWine
3 likes
MiceWine is a project that aims to run Windows applications and games on Android smartphones.
46 MiceWine alternatives
Cost / License
Free
Open Source (MIT)
Application type
Compatibility Layer Tool
Origin
Netherlands
EU
Platforms
Android
Android Tablet
Is MiceWine a good alternative to Wine PyQt5?