The best alternative to VueScan is XSane, which is both free and Open Source. If that doesn't suit you, our users have ranked more than 25 alternatives to VueScan and five of them are so hopefully you can find a suitable replacement. Other interesting alternatives to VueScan are SilverFast, Skanlite, Skanpage and WinScan2PDF.
XSane is a graphical scanning front-end for SANE (Scanner Access Now Easy). It uses the SANE-library to talk to scanners. It is designed for acquiring images with scanners (there are other devices like cameras and videodevices supported by SANE and you will see that xsane may...
Digitally archive, scan, and optimize photos with tools for advanced correction, batch jobs, printer calibration, real-time previews, and QuickTime tutorials. Works as stand-alone or Photoshop plug-in and supports over 340 scanner models for professionals and beginners.
Skanlite is a simple image scanning application to scan and save images. Skanlite is based on libksane, an interface for SANE library to control image scanners.
Skanpage is a simple scanning application designed for multi-page scanning and saving of documents and images.
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Siverfast has a comprehensive set of features. For negative and slide scanning it has tailored imaging profiles for different brands and types of film.